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In group a n 36 , the patients were directly taken for surgery, while in group b n 36 , patients were put on preoperative albendazole therapy for 12 weeks with subsequent surgery, followed by postoperative course of albendazole for another 12 weeks.
Following administration of albenza chewable tablets, average maximal plasma concentrations of albendazole sulfoxide were 804 ng ml range 202 to 2244 ng ml and 218 ng ml range 54 to 592 ng ml in the fed and fasted states, respectively.
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While oxidation to albendazole sulfoxide by fmo produces r enantiomers, while oxidation the cytochromes and by some enzymes in the gut epithelium produce s – .
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As demonstrated by experiments in animals, praziquantel and albendazole are effective antiparasitic drugs against t.
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